Between January 1 and April 14, 2026, 290 cases of invasive meningococcal disease were reported in Tashkent, Uzbekistan, with 24 deaths. The case fatality rate was 9.2% for cases with known outcomes. The most common symptoms were fever and hemorrhagic rash (56.9%), loss of consciousness (55.9%), and vomiting (55.5%). Mortality was significantly higher in patients with meningeal signs. 187 cases were microbiologically confirmed. Vaccination and chemoprophylaxis measures were implemented.
