DRC (Kasaï) — Ebola outbreak declared (September 4, 2025)

September 5, 2025

Summary. Health authorities in the Democratic Republic of the Congo have declared an Ebola virus disease (EVD) outbreak in Kasaï Province, with 28 suspected cases and 15 deaths (including 4 healthcare workers) reported as of September 4, 2025. The affected health zones are Bulape and Mweka. Laboratory confirmation was made on September 3 at the National Institute of Biomedical Research (INRB) in Kinshasa; the identified strain is Zaire ebolavirus (EBOV).

Where

  • Country: Democratic Republic of the Congo (DRC)
  • Province: Kasaï (south)
  • Health zones: Bulape and Mweka

Epidemiological situation (as of 04-09-2025)

  • 28 suspected cases and 15 deaths (4 among healthcare workers)
  • Reported symptoms: fever, vomiting, diarrhea, and hemorrhage
  • Lab confirmation: INRB (Kinshasa), September 3; Zaire ebolavirus
  • Expected trend: case numbers may rise while transmission continues

Response underway

  • National rapid response team deployed with WHO support (epidemiology, IPC, laboratory, case management)
  • Logistics: delivery of 2 tons of supplies (PPE, mobile lab, medical equipment). Hard-to-reach area: at least one day by road from Tshikapa; limited air links
  • Ring vaccination: 2,000 doses of Ervebo pre-positioned in Kinshasa for contacts and frontline HCWs
  • Continental support: Africa CDC confirming the declaration (Sept 4) and deploying experts for surveillance, contact tracing, laboratory, and IPC

Risk for travellers

  • Very low for tourists and business travellers outside affected areas and without exposure to healthcare settings or traditional funerals
  • High for healthcare workers and contacts of cases in areas with active transmission

Recommendations for travellers

  • Avoid travel to Bulape and Mweka while investigations and response are ongoing
  • Do not participate in funeral rites involving body contact; avoid bushmeat
  • Strict hand hygiene; avoid contact with bodily fluids and potentially contaminated objects
  • If fever or compatible symptoms occur within 21 days after visiting the area: self-isolate and seek medical care immediately, disclosing travel history

Recommendations for healthcare professionals (IVC, primary care, hospital)

  • Triage and report immediately any compatible case with recent travel/stay in Kasaï (Bulape/Mweka) during Aug–Sep 2025
  • Standard + contact + droplet precautions with eye protection; for aerosol-generating procedures, use FFP2/FFP3 and reinforced IPC measures
  • Isolate suspected cases; ensure safe handling of fluids and waste
  • Coordinate with public health for contact tracing and assessment of ring vaccination (Ervebo) when indicated

Context

  • Previous DRC Ebola outbreak: Équateur, April 2022, contained in <3 months
  • Kasaï recorded outbreaks in 2007 and 2008
  • The DRC has seen 15 outbreaks since 1976

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